{"id":1160,"date":"2015-01-15T11:50:46","date_gmt":"2015-01-15T11:50:46","guid":{"rendered":"http:\/\/nextmovesoftware.com\/blog\/?p=1160"},"modified":"2015-06-22T16:37:32","modified_gmt":"2015-06-22T15:37:32","slug":"coming-soon-matsy-in-stardrop","status":"publish","type":"post","link":"https:\/\/nextmovesoftware.com\/blog\/2015\/01\/15\/coming-soon-matsy-in-stardrop\/","title":{"rendered":"Coming soon: Matsy in StarDrop"},"content":{"rendered":"<p>For the last few months, we have been working together with <a href=\"http:\/\/www.optibrium.com\">Optibrium<\/a> to integrate <a href=\"http:\/\/www.nextmovesoftware.com\/matsy.html\">Matsy<\/a> into their <a href=\"http:\/\/www.optibrium.com\/stardrop\/\">StarDrop<\/a> platform for lead optimisation, the result of which will be released later this year:<br \/>\n<a href=\"http:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2015\/01\/StarDrop_Logo_300.png\"><img loading=\"lazy\" decoding=\"async\" src=\"\/blog\/wp-content\/uploads\/2015\/01\/StarDrop_Logo_300-300x104.png\" alt=\"StarDrop_Logo_300\" width=\"300\" height=\"104\" class=\"alignright size-medium wp-image-1164\" srcset=\"https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2015\/01\/StarDrop_Logo_300-300x104.png 300w, https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2015\/01\/StarDrop_Logo_300.png 400w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<blockquote><p>Optibrium\u2122 and NextMove Software, developers of software and chemoinformatics solutions for drug discovery, today announced an agreement to collaborate on the integration of NextMove Software\u2019s Matsy technology with Optibrium\u2019s StarDrop software suite. This combination will help to guide scientists\u2019 optimisation strategies to quickly identify compounds with a high chance of success for their drug discovery projects.<\/p>\n<p>The Matsy algorithm has been developed by NextMove Software to generate and search databases of matched molecular series to identify chemical substitutions that are most likely to improve target activity (<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm500022q\">J. Med. Chem., 2014, 57(6), pp 2704\u20132713<\/a>). This goes beyond conventional \u2018matched molecular pair analysis\u2019 by using data from longer series of matched compounds (and not just pairs) to make more relevant predictions for a particular chemical series of interest. As part of the collaboration with Optibrium, Matsy will be applied in StarDrop\u2019s Nova\u2122 module, which automatically generates new compound structures to stimulate the search for optimisation strategies related to initial hit or lead compounds. StarDrop\u2019s unique capabilities for multi-parameter optimisation and predictive modelling will enable efficient prioritisation of the resulting ideas to identify high quality compounds with the best chance of success.<\/p><\/blockquote>\n<p>For further information, see the full <a href=\"http:\/\/www.optibrium.com\/news\/pr\/Press%20Release%2015-01-15.pdf\">press release<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the last few months, we have been working together with Optibrium to integrate Matsy into their StarDrop platform for lead optimisation, the result of which will be released later this year: Optibrium\u2122 and NextMove Software, developers of software and chemoinformatics solutions for drug discovery, today announced an agreement to collaborate on the integration of &hellip; <a href=\"https:\/\/nextmovesoftware.com\/blog\/2015\/01\/15\/coming-soon-matsy-in-stardrop\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Coming soon: Matsy in StarDrop<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1160"}],"collection":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/comments?post=1160"}],"version-history":[{"count":5,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1160\/revisions"}],"predecessor-version":[{"id":1426,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1160\/revisions\/1426"}],"wp:attachment":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/media?parent=1160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/categories?post=1160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/tags?post=1160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}