{"id":1746,"date":"2016-03-21T12:29:36","date_gmt":"2016-03-21T12:29:36","guid":{"rendered":"https:\/\/nextmovesoftware.com\/blog\/?p=1746"},"modified":"2016-03-21T12:29:36","modified_gmt":"2016-03-21T12:29:36","slug":"sugarsplice-supports-pubchems-support-for-biologics","status":"publish","type":"post","link":"https:\/\/nextmovesoftware.com\/blog\/2016\/03\/21\/sugarsplice-supports-pubchems-support-for-biologics\/","title":{"rendered":"Sugar&#038;Splice supports PubChem&#8217;s support for biologics"},"content":{"rendered":"<p>Half a million molecules on PubChem have just had a new section added entitled &#8220;Biologic Description&#8221;. This includes a depiction of the oligomer structure and several line notations including IUPAC condensed and HELM, all of which were generated using Sugar&amp;Splice through perception from the all-atom representation. Since the original development of Sugar&amp;Splice was as part of a collaboration with PubChem, it is great to see these annotations finally appearing as part of this important resource.<\/p>\n<p>Previous <a href=\"https:\/\/nextmovesoftware.com\/blog\/2013\/07\/12\/pubchem-peptide-depictions\/\">blog<\/a> <a href=\"https:\/\/nextmovesoftware.com\/blog\/2015\/06\/23\/pubchem-peptide-depictions-part-2\/\">posts<\/a> have shown examples of the sorts of peptide depictions that Sugar&amp;Splice can generate. Here is how one appears on PubChem (<a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/118753634#section=Biologic-Description\">CID118753634<\/a>).<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1747\" src=\"https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-peptide.png\" alt=\"pubchem-peptide\" width=\"535\" height=\"768\" srcset=\"https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-peptide.png 535w, https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-peptide-209x300.png 209w\" sizes=\"(max-width: 535px) 100vw, 535px\" \/><\/p>\n<p>Sugar&#038;Splice also supports CFG-style depiction of oligosaccharides (<a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/71297593#section=Biologic-Description\">CID71297593<\/a>):<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1750\" src=\"https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-sacc.png\" alt=\"pubchem-sacc\" width=\"531\" height=\"785\" srcset=\"https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-sacc.png 531w, https:\/\/nextmovesoftware.com\/blog\/wp-content\/uploads\/2016\/03\/pubchem-sacc-203x300.png 203w\" sizes=\"(max-width: 531px) 100vw, 531px\" \/><\/p>\n<p>As ever, there is always more work to be done on improving depictions and perception, and we look forward to further increasing the coverage of biologics in PubChem over the coming months.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Half a million molecules on PubChem have just had a new section added entitled &#8220;Biologic Description&#8221;. This includes a depiction of the oligomer structure and several line notations including IUPAC condensed and HELM, all of which were generated using Sugar&amp;Splice through perception from the all-atom representation. Since the original development of Sugar&amp;Splice was as part &hellip; <a href=\"https:\/\/nextmovesoftware.com\/blog\/2016\/03\/21\/sugarsplice-supports-pubchems-support-for-biologics\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Sugar&#038;Splice supports PubChem&#8217;s support for biologics<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1746"}],"collection":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/comments?post=1746"}],"version-history":[{"count":6,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1746\/revisions"}],"predecessor-version":[{"id":1754,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/posts\/1746\/revisions\/1754"}],"wp:attachment":[{"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/media?parent=1746"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/categories?post=1746"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nextmovesoftware.com\/blog\/wp-json\/wp\/v2\/tags?post=1746"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}